Time spent preparing for practice paid off with a rewarding clinical director role.

Early in her career, vet Ami Sawran found comfort in academia, later feeling better prepared for practice life and taking up the role of clinical director with Westpoint Farm Vets in Chelmsford.

Survey of anthelmintic use in South American camelids in the UK.

BACKGROUND: Gastrointestinal helminths are common in South American camelids in the UK. However, there are no anthelmintics currently licenced for camelids, leading to a limited evidence base for treatment. The aim of this study was to assess the usage of anthelmintics among UK camelid farmers. METHODS: An online questionnaire focusing on the use of anthelmintics in camelids was distributed to UK camelid owners in Spring 2019. RESULTS: Forty-nine of the 51 respondents treated their camelids with anthelmintics, while 21 (42.0%) reported a previous gastrointestinal helminth diagnosis on their farms. A wide variety of anthelmintics were employed and there was striking variation in treatment frequency, dosage and source of information used to select anthelmintic dosing regimen. CONCLUSION: This work highlights the need for quality efficacy studies of anthelmintics in camelids to provide an appropriate evidence base for treatment, as well as the need for better education for camelid owners on anthelmintics and anthelmintic resistance.

Cellular localization of aquaporins along the secretory pathway of the lactating bovine mammary gland: an immunohistochemical study.

In this study we examined the cellular localization of aquaporins (AQPs) along the secretory pathway of actively lactating bovine mammary glands using immunohistochemistry. Mammary tissues examined included secretory ducts and acini, gland cisterns, teats, stromal and adipose tissues. Aquaporin 1 (AQP1) was localized in capillary endothelia throughout the mammary gland in addition to myoepithelial cells underlying teat duct epithelia. AQP2 and AQP6 were not detected and AQP9 was found only in leukocytes. AQP3 and AQP4 were observed in selected epithelial cells in the teat, cistern and secretory tubuloalveoli. AQP5 immunopositivity was prominent in the cistern. AQP3 and AQP7 were found in smooth muscle bundles in the teat, secretory epithelial cells and duct epithelial cells. These immunohistochemical findings support a functional role for aquaporins in the transport of water and small solutes across endothelial and epithelial barriers in the mammary gland and in the production and secretion of milk.